Stadium: Bryce Jordan Center
Home Manager: Reggie Witherspoon Away Manager: Micah Shrewsberry
| NCAAB | 2015/12/11 00:00 | Penn State v Canisius | L | 81-67 |
| NCAAB | 2007/11/16 12:00 | Penn State v Canisius | L | 93-40 |
| NCAAB | 2022/03/09 00:00 | Canisius v Fairfield | L | 50-72 |
| NCAAB | 2022/03/05 21:00 | Siena v Canisius | W | 64-67 |
| NCAAB | 2022/03/04 00:00 | Marist v Canisius | W | 67-78 |
| NCAAB | 2022/02/27 18:00 | Canisius v Quinnipiac | W | 72-67 |
| NCAAB | 2022/02/26 00:00 | Canisius v Iona | L | 65-72 |
| NCAAB | 2022/02/19 18:00 | Niagara v Canisius | L | 65-54 |
| NCAAB | 2022/02/15 00:00 | Canisius v Fairfield | L | 76-80 |
| NCAAB | 2022/02/13 00:00 | Canisius v Marist | L | 70-71 |
| NCAAB | 2022/03/12 02:00 | Penn State v Purdue | L | 61-69 |
| NCAAB | 2022/03/11 01:55 | Penn State v Ohio State | W | 71-68 |
| NCAAB | 2022/03/10 01:30 | Minnesota v Penn State | W | 51-60 |
| NCAAB | 2022/03/06 17:00 | Penn State v Rutgers | L | 58-59 |
| NCAAB | 2022/03/04 00:00 | Penn State v Illinois | L | 55-60 |
| NCAAB | 2022/02/28 00:00 | Nebraska v Penn State | L | 93-70 |
| NCAAB | 2022/02/26 00:00 | Northwestern v Penn State | W | 60-67 |
| NCAAB | 2022/02/22 00:00 | Penn State v Maryland | L | 61-67 |