Stadium: Sox Harrison Stadium Round: 1
| NCAAF | 2022/10/01 18:00 | Mercyhurst v Edinboro | W | 13-16 |
| NCAAF | 2021/10/16 16:00 | Edinboro v Mercyhurst | L | 20-27 |
| NCAAF | 2019/10/12 18:00 | Edinboro v Mercyhurst | L | 23-44 |
| NCAAF | 2018/10/06 16:00 | Mercyhurst v Edinboro | L | 24-6 |
| NCAAF | 2022/11/12 17:00 | Edinboro v Lock Haven | W | 26-13 |
| NCAAF | 2022/11/05 17:00 | Slippery Rock v Edinboro | L | 28-21 |
| NCAAF | 2022/10/29 16:00 | Edinboro v Seton Hill Griffins | L | 14-45 |
| NCAAF | 2022/10/22 16:00 | Clarion Golden Eagles v Edinboro | W | 17-47 |
| NCAAF | 2022/10/15 16:00 | Edinboro v Iup Crimson Hawks | L | 0-41 |
| NCAAF | 2022/10/08 18:00 | Edinboro v Gannon University Golden Knights | L | 17-35 |
| NCAAF | 2022/10/01 18:00 | Mercyhurst v Edinboro | W | 13-16 |
| NCAAF | 2022/09/24 16:00 | California Vulcans v Edinboro | L | 49-7 |
| NCAAF | 2022/11/12 17:00 | Mercyhurst v Bloomsburg Huskies | L | 13-16 |
| NCAAF | 2022/11/05 18:00 | Seton Hill Griffins v Mercyhurst | L | 7-0 |
| NCAAF | 2022/10/29 16:00 | Mercyhurst v California Vulcans | L | 20-44 |
| NCAAF | 2022/10/22 16:00 | Gannon University Golden Knights v Mercyhurst | L | 49-14 |
| NCAAF | 2022/10/15 22:00 | Mercyhurst v Clarion Golden Eagles | L | 21-23 |
| NCAAF | 2022/10/08 22:00 | Slippery Rock v Mercyhurst | L | 31-17 |
| NCAAF | 2022/10/01 18:00 | Mercyhurst v Edinboro | L | 13-16 |
| NCAAF | 2022/09/24 20:00 | Iup Crimson Hawks v Mercyhurst | L | 33-16 |